Bioanalytics
Our divsion of bioanalytics combines our expertise in biochemistry, molecular biology, as well as cell- and immune-biology. We offer, besides standard techniques, a specialized platform for testing biomolecules and their biological effects.
Nucleic Acid Analytics
- Identity and purity testing of nucleic acids by standard electrophoretic, PCR-based, spectroscopic and/or staining techniques
- Copy number determination of your target by Real-Time PCR
Protein/Peptide Analytics
- Protein purity and identity testing by electrophoretic techniques (Ph. Eur. 2.2.31, Ph. Eur. 2.2.54) and Western-Blot
- Protein Identity by AA COMPOSITION (Ninhydrin positive substances, Ph. Eur. 2.2.56)
- Amino Acid Analysis of raw materials (Ninhydrin positive substances, Ph. Eur. 2.2.56)
- Determination of protein concentration (Ph. Eur. 2.5.33) and ELISA techniques
Immune- and Cell Analytics
- Performance of analyte specific stability and proof of unwanted immunogenicity / PK-STUDIES (according to ICH M3, EMEA, FDA)
- Cytokine profiling (minimal sample amount and multiplexing)
- Immunoprofiling of PBMCS
- Enzyme-linked immunosorbent assays (ELISA)
- Flow Cytometry (Ph. Eur. 2.7.24)
Cell culture based bioassays and potency assays
- Performance of analyte specific cell effector assays (APOPTOSIS, ADCC, CDC)
- Proliferation/Reporter gene assays
- Implementation and performance of analyte specific in-vitro potency assays
- Assay of Heparin (Ph. Eur. 2.7.5)
TentaMedix offers you a diverse platform for the GMP compliant analytics of your biomolecule. From standard techniques to custom made bioassays. We support you on analytical method development, analytical method validation/verification/transfer, and on routine analysis of your test items.